Applications

Single-cell analysis, Stable isotope assimilation, Intracellular 2-D and 3-D mapping, Disease diagnosis, & more

Our Services

Customizable to fit your project's needs. Sample prep, Raman micro-spectroscopy, Atomic force microscopy

Achievements

Learn more about our major accomplishments since our establishment in 2014

Real-time Queue

Explore the current processing queue for our NARMIL research facility in real-time

Applications

Single-cell analysis, Stable isotope assimilation, Intracellular 2-D and 3-D mapping, Disease diagnosis, & more

Our Services

Customizable to fit your project's needs. Sample prep, Raman micro-spectroscopy, Atomic force microscopy

Achievements

Learn more about our major accomplishments since our establishment in 2014

Real-time Queue

Explore the current processing queue for our NARMIL research facility in real-time

NAno-RAMAN Molecular Imaging Laboratory

Our lab provides state-of-the-art instrumentation and expertise for analyses of single cells, aerosols, natural and engineered surfaces, minerals, biofilms, thin films, and novel synthetic materials. The lab’s vision is to offer unique analytical solutions to chronic limitations experienced in many research areas, to enable transformative discoveries, and to educate the next generation of scientists.

NARMIL is home to a Renishaw inVia Confocal Raman Microspectrometer and a Bruker Innova Atomic Force Microscope. These instruments can be operated independently or coupled for co-localization and Tip-enhanced Raman Scattering (TERS) and offer high performance, reliability, modular design, and user-friendly operating systems. The entire system is mounted on a floating 5’x8′ Newport INTEGRITY 3 vibration isolation table.

NARMIL Applications

Learn more about our diverse RAMAN applications that can be catered to your project's molecular imaging needs. Processes that can be explored by our methods are only limited by your imagination.

Intracellular mapping and analysis

Raman map of intracellular distributions of the lipid-like energy storage product, polyhydroxy-butyrate (red area with accompanying Raman spectrum) within a marine bacterium. Blue area is relatively rich in amino acids (blue spectrum) and proteins.

Cellular stable isotope assimilation

Examples of varying contributions of 12C-12C, 12C-13C, and 13C-13C isotopologues to shape, position, and areas of the n (C-C) and n (C=C) Raman spectral peaks for carotenoids of Synechococcus sp. cells assimilating varying amounts of DI13C.

Plastic polymer 3-D mapping

A. 3-D chemical maps of a composite microplastic particle produced by Raman microspectroscopic volume mapping. B. Section of 3-D chemical map of the microplastic particle generated from diagnostic peaks of polypropylene (red), phthalocyanine blue copper (cyan), and polyethylene (purple).